Results for Health
130,725 grants found
Showing 127,181 – 127,200 of 130,725 grants for "Health"
Clinical Validation Center for Hepatocellular Carcinoma
PROJECT SUMMARY Hepatocellular carcinoma (HCC) is one of the fastest-growing cause of cancer death in the U.S. and it is projected to be the 3rd leading cause of cancer death in th...
Discovery and manipulation of transcription factors to restore long term stem cell repopulation in aged bone-marrow
Project Summary Aging has a complex underlying biology characterized by a progressive loss of cellular and physiological function and this deterioration is strongly correlated with...
Clinical Validation Center for Hepatocellular Carcinoma
PROJECT SUMMARY Hepatocellular carcinoma (HCC) is one of the fastest-growing cause of cancer death in the U.S. and it is projected to be the 3rd leading cause of cancer death in th...
Summarizing Cardiac Data: An Automated Approach for Identifying Representative Heartbeats in the Clinical Setting
Project Summary/Abstract With a constant stream of patient data generated at the hospital bedside, clinicians are asked to interpret this data along with patient medical records an...
Development of a comprehensive suite of research-backed, integrated educational tools to inspire, educate, train, and support academic entrepreneurs in the commercialization of university research.
PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Resear...
Role of nociceptin-containing neurons of the lateral septum in binge-like alcohol consumption
PROJECT SUMMARY The COVID-19 pandemic has had a palpable impact on mental health, and maladaptive coping strategies, such as excessive alcohol consumption, have seen a marked incre...
Second Messenger Nucleotides of Enterococcus faecalis
ABSTRACT Enterococci are the 3rd most common cause of hospital-acquired infections and a major public health threat due to the continuous rise of multidrug-resistant (MDR) isolates...
Therapeutic Potentials of a New Long Noncoding RNA in Diabetic Bone Wound Repair
Patients with type 2 diabetes (T2D) have substantially higher incidence of bone disorders, including as much as a 64% greater risk of fracture as compared to those without T2D. Hig...
Repeated Administration of Cannabis Varying in THC and CBD: Effects on Abuse Liability, Experimental Pain and Plasma Endocannabinoids
The majority of the >1.2 million registered medical cannabis patients in the U.S. cite pain relief as their primary reason for using cannabis products. Although cannabis and its...
STARTUP Central
PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Resear...
Therapeutic Potentials of a New Long Noncoding RNA in Diabetic Bone Wound Repair
Patients with type 2 diabetes (T2D) have substantially higher incidence of bone disorders, including as much as a 64% greater risk of fracture as compared to those without T2D. Hig...
Regulation of zinc-dependent lysosome morphological restructuring, zinc trafficking and low zinc homeostasis in C. elegans and human model systems
Project Summary/Abstract Dysregulation of zinc homeostasis can lead to either zinc deficiency or zinc excess, resulting in a variety of human pathologies. Therefore, strict regulat...
A HANDS-FREE LUNG AND CARDIOVASCULAR ASSESSMENT DEVICE (LCAD) FOR THE REMOTE CARE OF PATIENTS WITH CHRONIC CARDIOPULMONARY CONDITIONS
PROJECT SUMMARY The goal of this project is to develop a remote, hands free self-auscultation and electrocardiogram (EKG) device for at home use in the remote monitoring and manage...
A HANDS-FREE LUNG AND CARDIOVASCULAR ASSESSMENT DEVICE (LCAD) FOR THE REMOTE CARE OF PATIENTS WITH CHRONIC CARDIOPULMONARY CONDITIONS
PROJECT SUMMARY The goal of this project is to develop a remote, hands free self-auscultation and electrocardiogram (EKG) device for at home use in the remote monitoring and manage...
Sepsis and the Systemic Cytokine Storm in Aging and Alzheimer Disease Models
ABSTRACT Severe infection and sepsis accelerate cognitive decline in older Americans, especially those with incipient Alzheimer's disease (AD). Sepsis is known to induce a sys...
Highly Sensitive and Robust Blood Test Platform for Screening and Early Detection of Alzheimer's Disease
With an effective treatment yet to be developed, early detection and surveillance of disease progression for Alzheimer’s disease (AD) and Alzheimer’s disease related dementias (ADR...
Tracking autobiographical thoughts: a smartphone-based approach to identifying cognitive correlates of Alzheimer's disease biomarkers and risk factors in clinically normal older adults
While the earliest phase of Alzheimer’s disease (AD) pathology is often described as “clinically silent”, prior work raises the possibility that early AD is associated with detecta...
Effects of NAD restoration on neurovascular coupling in community dwelling older adults
Age-related cognitive decline has emerged as one of the major public health challenges of our time. It is well known that normal cognitive function requires an adequate blood suppl...
Assessing Optimal XR-Buprenorphine Initiation Points in Jail
The prevalence of opioid use disorder (OUD) is especially high among individuals supervised by the criminal justice system (CJS), and a preponderance of opioid overdose deaths occu...
Antibiotic Model-Informed Precision Dosing in Critical Illness
PROJECT SUMMARY Pathophysiologic changes during critical illness can affect drug pharmacokinetics (PK, how the body affects the drug) and pharmacodynamics (PD, how the drug affects...