Results for Health
130,725 grants found
Showing 127,241 – 127,260 of 130,725 grants for "Health"
ASBMR Three Year Pre-Meeting Symposia
The American Society for Bone and Mineral Research (ASBMR), the largest professional, scientific and medical society established to bring together clinical and laboratory-based sci...
Longitudinal Impacts of Pandemic-Induced Disruptions on Adolescent Siblings' and Parents' Alcohol Use: A Family Life Course Perspective
PROJECT SUMMARY/ABSTRACT In March 2020, the COVID-19 pandemic abruptly disrupted the daily lives of adolescents and their families in the United States. Emergency school and commun...
Development of Blood-based Circular RNA Biomarkers for Alzheimer's Disease
PROJECT SUMMARY—This Phase I application targets PAS-19-316 to address the priorities for a) new, cost- effective, minimally-invasive biomarkers that could be used for screening an...
Computer-based Learning to Enhance ADRD Care in Prison: Just Care for Dementia
Project Summary/Abstract U.S. prison systems face sharply increased demands in caring for older people living in prisons. Alzheimer's Disease and related dementias (ADRD) are...
Longitudinal Impacts of Pandemic-Induced Disruptions on Adolescent Siblings' and Parents' Alcohol Use: A Family Life Course Perspective
PROJECT SUMMARY/ABSTRACT In March 2020, the COVID-19 pandemic abruptly disrupted the daily lives of adolescents and their families in the United States. Emergency school and commun...
Increasing Access to Genetic Testing in Underserved Patients Using a Multilingual Conversational Agent
ABSTRACT Background. The volume of patients who meet national criteria for germline genetic testing based on a cancer diagnosis alone, regardless of family history (i.e. ovarian, p...
Mapping membrane protein dynamics in time and space with mass spectrometry
The advancement of new analytical tools and methods are at the centre of tackling the biggest challenges in the life sciences. One such unmet challenge is understanding the structu...
Brainstem circuitry for sleep-wake control
PROJECT SUMMARY/ABSTRACT It is now clear that poor sleep quality has dramatic health consequences, yet sleep medicine is still in great need for safe and efficient sleep aids. Rece...
Single gene inborn errors of immunity underlying SARS-CoV-2-related multisystem inflammatory syndrome in children: a new approach to tackle a seemingly old puzzle
Project Summary A novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been quickly spreading around the world since December 2019 and causing coron...
Computational approaches to characterize heterogeneity and improve risk stratification in complex disease phenotypes
PROJECT SUMMARY/ABSTRACT Recent technological breakthroughs have enabled the generation of clinical, environmental, and multi-omics data at an unprecedented scale, providing a comp...
Mechanisms of Vaccine Immunity against Coccidioidomycosis
ABSTRACTWe will exploit a live attenuated ∆cps1 (null) strain of Coccidiodes posadasii to vaccinate against coccidiodomycosis, andelucidate the mechanics by which the lung epitheli...
Ultra-processed food consumption, gut microbiota, and glucose homeostasis in mid-life adults
Project Summary Advancing age is associated with gut dysbiosis, low-grade chronic inflammation, progressive insulin resistance, and increased risk of type 2 diabetes (T2D). Prediab...
Ultra-processed food consumption, gut microbiota, and glucose homeostasis in mid-life adults
Project Summary Advancing age is associated with gut dysbiosis, low-grade chronic inflammation, progressive insulin resistance, and increased risk of type 2 diabetes (T2D). Prediab...
CAREER: Quantifying Adaptation and Recombination in Pathogen Populations
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).To usefully anticipate the evolution of pathogenic viruses and bacteria, quan...
HIV-induced monocyte and macrophage perturbations driving liver fibrogenesis
Abstract Liver disease in patients with HIV infection remains a major public health problem despite effective combination antiretroviral therapy (cART), and cART does not fully rev...
Short-term Outcome of Stimulant Use Disorder Treatment Trials
Project Summary Stimulant use disorders, including cocaine and methamphetamine use disorders, impact the lives of millions of Americans and are associated with significant health a...
Targeting polo-like kinase for therapy of small cell lung cancer
PROJECT SUMMARY/ABSTRACT Small cell lung cancer (SCLC) is a significant health problem projected to afflict more than 35,000 new patients in the US in 2021. Less than 20% of newly...
Understanding the Drivers of Antibiotic use in the Treatment of Childhood Diarrhea and Relationship to Antibiotic Resistance in China
ABSTRACT By the age of 5, children in low and middle-income countries (LMICs) are exposed to nearly five times more antibiotics than high-income country children. Although improved...
Understanding the Drivers of Antibiotic use in the Treatment of Childhood Diarrhea and Relationship to Antibiotic Resistance in China
ABSTRACT By the age of 5, children in low and middle-income countries (LMICs) are exposed to nearly five times more antibiotics than high-income country children. Although improved...
Platelet-mediated mechanisms of placental and systemic hypercoagulability in preeclampsia
PROJECT SUMMARY/ABSTRACT Preeclampsia (PE) remains a significant clinical and public health burden affecting 3-5% of all pregnancies worldwide, and is a leading cause of maternal a...