Results for Health
130,725 grants found
Showing 127,361 – 127,380 of 130,725 grants for "Health"
Supplement: SCH: Enabling Data Outsourcing and Sharing for AI-powered Parkinson's Research
Supplement Project Summary What does Project R01 LM014027-01 do? Artificial intelligence holds the promise of transforming data-driven biomedical research and computational health i...
A clinical prediction rule for identifying South African colorectal cancer patients who will fail to engage in oncology care
PROJECT SUMMARY/ABSTRACT Colorectal cancer (CRC) is an emerging public health problem in South Africa (SA).Preliminary research from KwaZulu-Natal (KZN), SA shows that 23% of newly...
University of Rochester Vaccine and Treatment Evaluation Unit (VTEU)
The Vaccine and Treatment Evaluation Units (VTEUs) are a critical resource for the NIAID Infectious Diseases Clinical Research Consortium to conduct clinical research and trials to...
Pharmacotherapy in conjunction with lifestyle counseling for management of weight regain after bariatric surgery (PROJECT-BARI)
Project Summary Although bariatric surgery is the most effective treatment for severe obesity, a large proportion of patients experience significant weight regain with longer follo...
Development of a model to implement guideline-concordant STI/HIV healthcare and screening for adolescents in the pediatric emergency department
Project summary Adolescents (13-17-year-olds) in the United States (US) are at high risk of acquiring sexually transmitted infections/diseases (STIs), such as chlamydia, gonorrhea,...
Structural and diffusion changes of perivascular space in aging, cognitive decline and Alzheimer's disease
PROJECT SUMMARY Perivascular spaces (PVS) are the area around arterioles, venules and capillaries which accommodate the clearance of the metabolic waste via Aquaporin-4 channels ex...
Evaluating the Blood-Brain Barrier Bioavailability and in vivo Efficacy Potential of a Novel TAK1 Inhibitor Targeting Chronic Pain
Project Summary / Abstract Chronic pain is a prevalent health concern, affecting up to 100 million people and carrying an economic burden up to $560 billion annually in the US alon...
Dietary Behaviors, The Food Environment and Sleep Duration Changes in Urban Children with Asthma
Project Summary / Abstract Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes sleep and asthma management. Further, this group suff...
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease
OVERALL – SUMMARY Alzheimer’s disease (AD) is a major unresolved public health problem. Efforts to prevent or stall this disease have failed, in good part because of inadequate und...
Understanding and Improving Inequities in Palliative Care for Older Adults with Advanced Dementia and Limited-English Proficiency: A Mixed-Methods Evaluation
PROJECT SUMMARY Older adults with Alzheimer's Disease and Related Dementias and limited-English proficiency (LEP) are at high risk of receiving suboptimal, goal-discordant car...
Testing a very low-carbohydrate diet version of the Diabetes Prevention Program to reduce risk factors for type 2 diabetes
ABSTRACT One-third of U.S. adults have prediabetes and are at high risk of developing type 2 diabetes and its devastating health consequences. The landmark Diabetes Prevention Prog...
Exosome biology in Alzheimer's disease and concussion
ABSTRACT Repeated concussions (mild Traumatic Brain Injury, mTBI), which are particularly prevalent in athletes and military personnel, can lead to long-term brain health issues in...
A Prospective Study Examining the Role of Gestational SSRI Exposure in the Development of Functional Gastrointestinal Disorders
Abstract Functional gastrointestinal disorders (FGIDs) are common, costly, and cause significant impairment that can begin in infancy. FGIDs remain poorly understood, and treatment...
A tailored exposure intervention targeting exercise anxiety and avoidance in cardiac rehabilitation
PROJECT SUMMARY/ABSTRACT Regular exercise and lifestyle physical activity (PA) are critical for quality of life and longevity among a growing aging population. Aging produces chang...
Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction
Project Summary/Abstract Heart failure (HF) is a major public health problem worldwide, and half of patients presenting with HF have preserved ejection fraction (HFpEF), rather tha...
Impact of Sleep Duration on Immune Balance in Urban Children with Asthma
Project Summary / Abstract Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes sleep and asthma management. Further, this group suff...
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease
OVERALL – SUMMARY Alzheimer’s disease (AD) is a major unresolved public health problem. Efforts to prevent or stall this disease have failed, in good part because of inadequate und...
Collaborative Research: Synthetic and Systems Biology Approaches to Semi-synthetic Cells with Expanded DNA Alphabets
This project focuses on novel forms of DNA that are not built only from the standard four nucleotides found in natural DNA, but with two or four additional nucleotides, to form an...
CAREER: A Research and Educational Framework for Incorporating Spatial Heterogeneity into Social Network Analysis
Social networks are representations of the relationships between individuals or groups, ranging from household ties in an isolated village to billions of online social media connec...
Sex Differences in the Clinical Expression of Alzheimer's Disease Neuropathology and Their Underlying Biological Mechanisms
PROJECT SUMMARY/ABSTRACT Sex differences in the risk of Alzheimer’s disease (AD) and AD pathology burden have been extensively studied; however, little is known about how AD pathol...