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Results for Health

130,725 grants found

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Showing 127,421127,440 of 130,725 grants for "Health"

Active NON-SBIR/STTR RPGS
A multidisciplinary approach to study ecotypes driving transmission and pathogenesis of Visceral Leishmaniasis (VL) and Post kala-azar dermal leishmaniasis (PKDL) in Eastern Africa
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Ohio State University United States 2022 – 2027

Abstract Over 12 million people currently suffer from leishmaniasis, and ~2 million new cases occur each year, making it a major global health problem and a WHO classified neglecte...

$4.37M
USD
Active NON-SBIR/STTR RPGS
Initiation of immune responses to SARS COV2 in the oral cavity and upper airway
NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEAR... University of Mississippi Med Ctr United States 2022 – 2027

Abstract Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a life-threatening illness with multi-system involv...

$8.22M
USD
Completed NON-SBIR/STTR RPGS
QBSafe: a randomized trial of a novel intervention to improve care for people living with type 2 diabetes.
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Yale University United States 2022 – 2025

PROJECT ABSTRACT: Clinical guidelines, performance measures, and clinical trials for patients with type 2 diabetes mellitus (DM2) have traditionally focused on achieving certain le...

$3.05M
USD
Active OTHER RESEARCH-RELATED
Unraveling the Role of PD-1 in CD8+ Tissue-Resident Memory T Cell Homeostasis and Epithelial Damage in Human Colitis
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Massachusetts General Hospital United States 2022 – 2027

Project Summary Monoclonal antibodies against co-inhibitory immune receptors PD-1 and CTLA-4 [immune checkpoint inhibitors (ICIs)] have revolutionized immuno-oncology by reversing...

$1.72M
USD
Active NON-SBIR/STTR RPGS
A Multicenter Randomized Controlled Trial of a Patient Safety Reporting Intervention for Families to Improve Medical Error Detection and Reduce Inequities
AGENCY FOR HEALTHCARE RESEARCH AND QUALITY Boston Children'S Hospital United States 2022 – 2027

PROJECT SUMMARY/ABSTRACT Hospitals ineffectively examine the safety of their processes by relying on voluntary incident reporting (VIR) by clinical staff who are overworked and afr...

$3.98M
USD
Completed NON-SBIR/STTR RPGS
Investigating virulence functions of mastitis-associated Extraintestinal pathogenic Escherichia coli relevant to human disease
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Brigham Young University United States 2022 – 2025

Abstract/Project Summary Extraintestinal Escherichia coli (ExPEC) are bacteria that live in the intestines of mammals and cause life- threatening illnesses when they infect other t...

$3.79M
USD
Completed NON-SBIR/STTR RPGS
Mechanisms of oxygen off-loading from red blood cells in murine models of human disease
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Case Western Reserve University United States 2022 – 2025

Red blood cells (RBCs) play a vital role in gas transport—carrying O2 from the alveolar air to systemic tissues, and CO2 in the opposite direction. Their task is central to many di...

$6.65M
USD
Completed NON-SBIR/STTR RPGS
Mechanisms of oxygen off-loading from red blood cells in murine models of human disease
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Case Western Reserve University United States 2022 – 2025

Red blood cells (RBCs) play a vital role in gas transport—carrying O2 from the alveolar air to systemic tissues, and CO2 in the opposite direction. Their task is central to many di...

$6.58M
USD
Completed OTHER RESEARCH-RELATED
Protein-driven dynamics of pre-mRNA splicing catalysis through single molecule microscopy
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Michigan At Ann Arbor United States 2022 – 2023

Project Summary In eukaryotic organisms, transcribed RNA is processed from precursor messenger RNA (pre-mRNA) into mature RNA in a process known as splicing. During this RNA proces...

$729.2K
USD
Completed NON-SBIR/STTR RPGS
Fetal MRI: robust self-driving brain acquisition and body movement quantification
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOEN... Boston Children'S Hospital United States 2022 – 2025

PROJECT SUMMARY/ ABSTRACT Our premise is that the fetal stage of human brain development is the most dynamic, the most vulnerable and the most important for lifelong behavioral and...

$7.29M
USD
Active NON-SBIR/STTR RPGS
Novel HCV vaccine antigens and nanoparticles
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Scripps Research Institute, The United States 2022 – 2027

Project Summary Hepatitis C virus (HCV) infects 1-2% of the world population and poses a significant threat to public health. Recent studies have identified a panel of broadly neut...

Completed NON-SBIR/STTR RPGS
Investigation into the Endogenous Ligand Repertoire of the Non-Classical MHC-Related Protein, MR1 in Multiple Myeloma Cell Lines
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Chicago United States 2022 – 2024

Project Abstract: Major Histocompatibility Complex (MHC) molecules have been long been appreciated as the bridge between the innate and adaptive immune cell populations. Beyond the...

$1.98M
USD
Active NON-SBIR/STTR RPGS
Protein-driven dynamics of pre-mRNA splicing catalysis through single molecule microscopy
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Alabama At Birmingham United States 2022 – 2026

Project Summary In eukaryotic organisms, transcribed RNA is processed from precursor messenger RNA (pre-mRNA) into mature RNA in a process known as splicing. During this RNA proces...

$2.49M
USD
Completed NON-SBIR/STTR RPGS
Fetal MRI: robust self-driving brain acquisition and body movement quantification
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOEN... Boston Children'S Hospital United States 2022 – 2025

PROJECT SUMMARY/ ABSTRACT Our premise is that the fetal stage of human brain development is the most dynamic, the most vulnerable and the most important for lifelong behavioral and...

$6.78M
USD
Active NON-SBIR/STTR RPGS
Protein-driven dynamics of pre-mRNA splicing catalysis through single molecule microscopy
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Alabama At Birmingham United States 2022 – 2026

Project Summary In eukaryotic organisms, transcribed RNA is processed from precursor messenger RNA (pre-mRNA) into mature RNA in a process known as splicing. During this RNA proces...

$2.49M
USD
Completed STANDARD GRANT
RII Track-4:NSF: Amplification of drought effects on vegetation by anthropogenic warming
National Science Foundation (US University of Iowa United States 2022 – 2024

Droughts are among the world’s costliest natural disasters, causing severe damage to both social and ecological systems. Human-caused warming increases the “dryness” of the atmosph...

$2.2M
USD
Active NON-SBIR/STTR RPGS
Function of T cells at the Maternal-Fetal Interface
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Yale University United States 2022 – 2026

Project Summary: Over the past five years, the leading cause of death worldwide for children under five has been complications from preterm birth (PTB) (

$6.73M
USD
Active NON-SBIR/STTR RPGS
Function of T cells at the Maternal-Fetal Interface
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Yale University United States 2022 – 2026

Project Summary: Over the past five years, the leading cause of death worldwide for children under five has been complications from preterm birth (PTB) (

$6.77M
USD
Completed NON-SBIR/STTR RPGS
Function of T cells at the Maternal-Fetal Interface
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Yale University United States 2022 – 2025

Project Summary: Over the past five years, the leading cause of death worldwide for children under five has been complications from preterm birth (PTB) (

$739K
USD
Completed TRAINING, INDIVIDUAL
Clinical and Psychosocial Predictors of Post-event Processing in Adults who Stutter
NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICA... University of Texas At Austin United States 2022 – 2024

Project Abstract Stuttering is a neurophysiological disorder that is genetically transmitted, yet, there is a pervasive assumption that stuttering is the result of being nervous or...

$392.5K
USD