Results for Health
130,725 grants found
Showing 127,461 – 127,480 of 130,725 grants for "Health"
Caregiving, Complex Family and Kinship Ties, and Alzheimer's Disease and Related Dementias (ADRD)
Families and unpaid caregivers provide the majority of assistance to older Americans living with limitations in the U.S. Those living with Alzheimer’s Disease and Related Dementias...
Immune response and viral dynamics within the female genital tract during hyperacute and acute HIV infection
Project Summary HIV remains a global epidemic and, in the areas of greatest prevalence, disproportionately infects young women. However, most studies of hyperacute and acute HIV in...
Deciphering the progression and regulation of human translesion DNA synthesis
Project Summary/Abstract The overarching goal of my research program is to understand how the human genome is faithfully replicated when it is constantly damaged by covalent modifi...
C-DIAS RP 2: Implementing contingency management for stimulant use in specialty addiction treatment organizations
C-DIAS RESEARCH PROJECT 2: PROJECT SUMMARY/ABSTRACT This rigorous experiment addresses a critical public health problem--the rising stimulant/opioid epidemic. It advances implement...
Bridges to the Baccalaureate Research Training Program at the University of Kansas/Haskell Indian Nations University
PROJECT SUMMARY The Haskell-KU Bridge V Program supports students from Haskell Indian Nations University who seek to develop careers in biomedical, bioengineering, behavioral and e...
A human translation of research on the neurobehavioral reward and reinforcement of flavored electronic nicotine delivery systems (ENDS)
Abstract Of the more than 10 million people in the United States using electronic nicotine delivery systems (ENDS), the vast majority are using e-liquids with non-tobacco flavors....
Quantifying effects of comorbidities and genetics on cannabinoid exposure in the elderly
Project summary/abstract Americans ≥65-years represent a growing segment of the US population who use cannabis for multiple ailments, increasing about two-fold from 2015 to 2018. D...
Antibiotic Model-Informed Precision Dosing in Critical Illness
PROJECT SUMMARY Pathophysiologic changes during critical illness can affect drug pharmacokinetics (PK, how the body affects the drug) and pharmacodynamics (PD, how the drug affects...
Assessing Optimal XR-Buprenorphine Initiation Points in Jail
The prevalence of opioid use disorder (OUD) is especially high among individuals supervised by the criminal justice system (CJS), and a preponderance of opioid overdose deaths occu...
Reduction of opioid requirement associated with Auriculo-nerve stimulation following open surgery
PROJECT SUMMARY: Perioperative prescription of opioids is an important contributor to the current opioid epidemic, affecting ~4% of >50 million Americans undergoing surgery each...
Pragmatic Trial
PROJECT SUMMARY/ABSTRACT The centerpiece of the MATCHES Center is a pragmatic trial, MATCH-UP (MAking Telehealth-delivery of Cancer Care at Home—Upscaled Services Protocol), which...
Clinical Practice Network
PROJECT SUMMARY/ABSTRACT The purpose of the Clinical Practice Network (CPN) of the MATCHES Telehealth Research Center is to provide the environment for conducting and evaluating th...
IntBIO: Collaborative Research: Integrated mechanisms of environment-host-virome interactions
In nature, encounters between humans and wildlife correlate with greater viral burdens in wildlife and therefore with higher risk of new viral pathogens spilling over into human po...
CAREER: Disentangled learning of high dimensional biomedical data in the presence of inherent heterogeneity
The advancement in high throughput technologies is revolutionizing the fields of biomedical research, giving rise to large-scale patient-derived molecular datasets, including match...
IntBIO: Collaborative Research: Integrated mechanisms of environment-host-virome interactions
In nature, encounters between humans and wildlife correlate with greater viral burdens in wildlife and therefore with higher risk of new viral pathogens spilling over into human po...
LEAP-HI: US-Ireland R&D Partnership: Control Co-Design for Ocean Wave Energy Conversion
The United Nations has designated the 2020s as the “Decade of Ocean Science for Sustainable Development”. Along the long coastlines of the US, Ireland, and the UK, ocean waves repr...
Understanding aquaporin-4 relocalisation in the central nervous system
The human body is approximately 60% water, as such, control of the water content of different parts of our body is vital for health. Osmosis is the fundamental process by which wat...
The Role of Creb5 in Maintaining Synovial Joint Homeostasis
Project Summary/Abstract. The broad, long-term goal of this project is to develop a comprehensive understanding of the regulatory network that regulates the differentiation and mai...
Mapping the Time Course of mTORC1-Driven Tumorigenesis in the Developing Brain
SUMMARY The mammalian target of rapamycin complex 1 (mTORC1) signaling pathway regulates cell size and growth and is frequently mutated in disease, including in a class of neurodev...
Implementation of emergency department screening to impact rising syphilis rates in vulnerable populations
PROJECT SUMMARY Syphilis rates in the U.S. have been increasing steadily since 2001, with more than 130,000 new cases reported in 2019. Left untreated, syphilis can lead to neurolo...