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Results for Health

130,725 grants found

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Showing 127,501127,520 of 130,725 grants for "Health"

Active NON-SBIR/STTR RPGS
hHv1 channels in neutrophils and the innate immune inflammatory response
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of California-Irvine United States 2022 – 2026

SUMMARY/ABSTRACT (30 lines) Relevance to public health. Polymorphonuclear leukocytes (PMN, neutrophils) release reactive oxygen species (ROS) to combat infection, but this inflamma...

$6.01M
USD
Active NON-SBIR/STTR RPGS
Is the gut important in multiple joint osteoarthritis? A multimodal investigation in humans and pet dogs
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETA... University of North Carolina Chapel Hill United States 2022 – 2027

Project Summary The central hypothesis of this work is that increased intestinal permeability (IP), either directly, or via related comorbidities, promotes the development and wors...

$6.48M
USD
Active NON-SBIR/STTR RPGS
hHv1 channels in neutrophils and the innate immune inflammatory response
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of California-Irvine United States 2022 – 2026

SUMMARY/ABSTRACT (30 lines) Relevance to public health. Polymorphonuclear leukocytes (PMN, neutrophils) release reactive oxygen species (ROS) to combat infection, but this inflamma...

$5.86M
USD
Completed OTHER RESEARCH-RELATED
Evaluation of the SCALED (SCaling AcceptabLE cDs) Approach for the Implementation of Interoperable CDS for Venous Thromboembolism Prevention
AGENCY FOR HEALTHCARE RESEARCH AND QUALITY University of Minnesota United States 2022 – 2025

ABSTRACT/PROJECT SUMMARY There is a global emphasis and critical need to close the patient-centered outcomes research (PCOR) evidence to practice gap. Forty percent of patients do...

$9.75M
USD
Completed NON-SBIR/STTR RPGS
Daily personalized drinking feedback delivered via mobile phone
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Brown University United States 2022 – 2025

PROJECT SUMMARY Many young adults engage in heavy drinking and in turn experience negative consequences (e.g., severe injury, overdose). While personalized feedback interventions (...

$2.29M
USD
Active NON-SBIR/STTR RPGS
The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation.
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of California, San Francisco United States 2022 – 2027

PROJECT ABSTRACT Lung transplantation aims to extend survival, relieve disability, and improve health-related quality of life (HRQL). Although many do well, perioperative complicat...

$4.19M
USD
Active NON-SBIR/STTR RPGS
The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation.
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of California, San Francisco United States 2022 – 2027

PROJECT ABSTRACT Lung transplantation aims to extend survival, relieve disability, and improve health-related quality of life (HRQL). Although many do well, perioperative complicat...

$1.74M
USD
Active NON-SBIR/STTR RPGS
Discovery and manipulation of transcription factors to restore long term stem cell repopulation in aged bone-marrow
NATIONAL INSTITUTE ON AGING Massachusetts Institute of Technology United States 2022 – 2027

Project Summary Aging has a complex underlying biology characterized by a progressive loss of cellular and physiological function and this deterioration is strongly correlated with...

$6.02M
USD
Active NON-SBIR/STTR RPGS
Type-I Interferons drive cell-autonomous immunity to malaria
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Georgia United States 2022 – 2027

PROJECT SUMMARY Malaria, caused by the protozoan Plasmodium is a devastating disease that kills close to half a million people each year. Plasmodium transmitted by mosquitoes under...

$3.78M
USD
Completed NON-SBIR/STTR RPGS
Antibiotic resistance among hypermutator carbapenem resistant Klebsiella pneumoniae
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Pittsburgh At Pittsburgh United States 2022 – 2024

Project Summary Carbapenem resistant Enterobacteriaceae (CRE) are major public health threats. CR-Klebsiella pneumoniae (CRKP) are the most common CRE globally. Treatment of CRKP a...

$2.6M
USD
Active NON-SBIR/STTR RPGS
Determining the performance and accuracy of SILVAMP TB LAM and cost-effectiveness of diagnostic testing for TB meningitis.
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Kansas Medical Center United States 2022 – 2027

Project Summary Tuberculous meningitis (TBM) is the second most common cause of meningitis in Sub-Saharan Africa. Neurologic disability and mortality are common, mortality is at le...

$6.64M
USD
Completed NON-SBIR/STTR RPGS
Determining the performance and accuracy of SILVAMP TB LAM and cost-effectiveness of diagnostic testing for TB meningitis.
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Kansas Medical Center United States 2022 – 2023

Project Summary Tuberculous meningitis (TBM) is the second most common cause of meningitis in Sub-Saharan Africa. Neurologic disability and mortality are common, mortality is at le...

$2.86M
USD
Active NON-SBIR/STTR RPGS
Type-I Interferons drive cell-autonomous immunity to malaria
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Georgia United States 2022 – 2027

PROJECT SUMMARY Malaria, caused by the protozoan Plasmodium is a devastating disease that kills close to half a million people each year. Plasmodium transmitted by mosquitoes under...

$3.78M
USD
Completed NON-SBIR/STTR RPGS
Antibiotic resistance among hypermutator carbapenem resistant Klebsiella pneumoniae
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Pittsburgh At Pittsburgh United States 2022 – 2025

Project Summary Carbapenem resistant Enterobacteriaceae (CRE) are major public health threats. CR-Klebsiella pneumoniae (CRKP) are the most common CRE globally. Treatment of CRKP a...

$2.06M
USD
Active NON-SBIR/STTR RPGS
Determining the performance and accuracy of SILVAMP TB LAM and cost-effectiveness of diagnostic testing for TB meningitis
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Minnesota United States 2022 – 2027

Project Summary Tuberculous meningitis (TBM) is the second most common cause of meningitis in Sub-Saharan Africa. Neurologic disability and mortality are common, mortality is at le...

$3.61M
USD
Active NON-SBIR/STTR RPGS
Type-I Interferons drive cell-autonomous immunity to malaria
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Georgia United States 2022 – 2027

PROJECT SUMMARY Malaria, caused by the protozoan Plasmodium is a devastating disease that kills close to half a million people each year. Plasmodium transmitted by mosquitoes under...

$3.78M
USD
Active NON-SBIR/STTR RPGS
Determining the performance and accuracy of SILVAMP TB LAM and cost-effectiveness of diagnostic testing for TB meningitis
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Minnesota United States 2022 – 2027

Project Summary Tuberculous meningitis (TBM) is the second most common cause of meningitis in Sub-Saharan Africa. Neurologic disability and mortality are common, mortality is at le...

$7.32M
USD
Active NON-SBIR/STTR RPGS
Ending HIV: Bringing Integrated Prevention and Treatment Services to People Who Use Drugs Where They Live
NATIONAL INSTITUTE ON DRUG ABUSE Yale University United States 2022 – 2027

Project Abstract: The United States (U.S.) Ending the HIV Epidemic (EHE) plan’s primary goal is to reduce the number of new HIV infections by 90% by 2030, but this will not happen...

$11.73M
USD
Completed STANDARD GRANT
Developing a Statewide Professional Development Network for Effective Teaching of Undergraduate Quantitative Reasoning Course
National Science Foundation (US Ohio University United States 2022 – 2026

This project will serve the national interest by improving instruction in introductory quantitative literacy courses intended for undergraduates pursuing degrees outside of STEM. Q...

$3M
USD
Completed OTHER RESEARCH-RELATED
Identifying the role of the gut microbiome in the etiology of benign breast disease
NATIONAL CANCER INSTITUTE Brigham and Women'S Hospital United States 2022 – 2023

PROJECT SUMMARY/ABSTRACT The overall goal of this project is to identify the role of the gut microbiome in the etiology of benign breast disease (BBD), and thereby shed light on it...

$1.69M
USD