Results for Health
130,725 grants found
Showing 127,541 – 127,560 of 130,725 grants for "Health"
ACE2-targeted PET radiotracers for investigating spatiotemporal distribution of SARS-CoV-2 organ injury and therapy response.
PROJECT SUMMARY: The COVID-19 pandemic, caused by the new coronavirus SARS-CoV-2, has had a remarkable impact on public health worldwide with the largest number of cases and deaths...
A multiscale approach for elucidating nuclear entry mechanisms of HIV-1 capsid
Project Summary Human immunodeficiency virus type 1 (HIV-1) remains a major threat to global health. Therefore, it is essential that we fully understand the mechanism of viral infe...
ACE2-targeted PET radiotracers for investigating spatiotemporal distribution of SARS-CoV-2 organ injury and therapy response.
PROJECT SUMMARY: The COVID-19 pandemic, caused by the new coronavirus SARS-CoV-2, has had a remarkable impact on public health worldwide with the largest number of cases and deaths...
A multiscale approach for elucidating nuclear entry mechanisms of HIV-1 capsid
Project Summary Human immunodeficiency virus type 1 (HIV-1) remains a major threat to global health. Therefore, it is essential that we fully understand the mechanism of viral infe...
Genetic and Genomic Analysis of Starvation Resistance in C. elegans
PROJECT SUMMARY By governing growth and quiescence, nutrient-responsive pathways are central to cancer, diabetes and aging. The function of these pathways in starvation informs und...
Identification of Precision Sepsis Subphenotypes Using Vital Sign Trajectories
Project Abstract The scientific goal of this K23 is to apply cutting-edge data science approaches to identify novel subphenotypes within the heterogeneous sepsis syndrome. This K23...
Harnessing Data Science to Promote Equity in Injury and Surgery for Africa
Project Summary The Data Science Center for the Study of Surgery, Injury, and Equity in Africa (D-SINE-Africa) is an NIH U54- funded research hub located at the University of Buea...
Impact of Music Improvisation Training on Brain Function and Cognition among Older Adults
ABSTRACT Approximately 5.8 million adults age 60 and over in the United States live with Alzheimer disease and related dementias (AD/ADRD) at a cost of $290 billion per year. Older...
Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa
Project Summary/Abstract Sickle cell anemia (SCA) is among the world’s most common and devastating blood disorders, affecting more than 300,000 newborns per year. The majority of i...
Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa
Project Summary/Abstract Sickle cell anemia (SCA) is among the world’s most common and devastating blood disorders, affecting more than 300,000 newborns per year. The majority of i...
Impact of Music Improvisation Training on Brain Function and Cognition among Older Adults
ABSTRACT Approximately 5.8 million adults age 60 and over in the United States live with Alzheimer disease and related dementias (AD/ADRD) at a cost of $290 billion per year. Older...
Identification of Precision Sepsis Subphenotypes Using Vital Sign Trajectories
Project Abstract The scientific goal of this K23 is to apply cutting-edge data science approaches to identify novel subphenotypes within the heterogeneous sepsis syndrome. This K23...
Genetic and Genomic Analysis of Starvation Resistance in C. elegans
PROJECT SUMMARY By governing growth and quiescence, nutrient-responsive pathways are central to cancer, diabetes and aging. The function of these pathways in starvation informs und...
Clinical and immunologic factors underlying heart failure with preserved ejection fraction among persons with HIV in South Africa
Premise: HIV associated CVD is a significant cause of clinical morbidity and a barrier to successful aging among persons living with HIV (PWH). To date, HIV-CVD research has emphas...
A Squirrel Monkey Model of Alzheimer’s Disease: Developing Behavioral, Blood, and CSF Biomarkers
Project Summary Alzheimer’s disease (AD) is a major health concern defined by pathologic changes in the brain that produce altered behavior and cognitive function. There is a need...
A Novel Instrument to Address Freezing of Gait in Parkinson's Patients
Project Summary/Abstract Introduction. Parkinson’s Disease (PD) is a common neurodegenerative disorder that affects 1 million Americans and 10 million individuals worldwide. One of...
Clinical and immunologic factors underlying heart failure with preserved ejection fraction among persons with HIV in South Africa
Premise: HIV associated CVD is a significant cause of clinical morbidity and a barrier to successful aging among persons living with HIV (PWH). To date, HIV-CVD research has emphas...
Systems-based screen of compounds that target nitrogen metabolism of Mycobacterium tuberculosis.
M. tuberculosis (Mtb), the etiological agent of TB, is presently the most devastating infectious agent of mortality worldwide, responsible for about 8 million cases of TB each year...
A Multi-Level Intervention to Promote Healthy Beverage Intake through Childcare
PROJECT SUMMARY There is little debate that sugar-sweetened beverages (SSBs; drinks with added sugar) lack nutrition, are a major source of added sugar and calories, and promote ob...
A Multi-Level Intervention to Promote Healthy Beverage Intake through Childcare
PROJECT SUMMARY There is little debate that sugar-sweetened beverages (SSBs; drinks with added sugar) lack nutrition, are a major source of added sugar and calories, and promote ob...