Results for Health
130,725 grants found
Showing 127,601 – 127,620 of 130,725 grants for "Health"
Testing a very low-carbohydrate diet version of the Diabetes Prevention Program to reduce risk factors for type 2 diabetes
ABSTRACT One-third of U.S. adults have prediabetes and are at high risk of developing type 2 diabetes and its devastating health consequences. The landmark Diabetes Prevention Prog...
A Prospective Study Examining the Role of Gestational SSRI Exposure in the Development of Functional Gastrointestinal Disorders
Abstract Functional gastrointestinal disorders (FGIDs) are common, costly, and cause significant impairment that can begin in infancy. FGIDs remain poorly understood, and treatment...
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease
OVERALL – SUMMARY Alzheimer’s disease (AD) is a major unresolved public health problem. Efforts to prevent or stall this disease have failed, in good part because of inadequate und...
The Role of RBC Reactive Oxygen Species in Regulating Thrombotic Events During Aging
The Role of RBC Reactive Oxygen Species in Regulating Thrombotic Events During Aging Abstract: Seventy percent of mid-life stage (older) adults have already been diagnosed with at...
A Prospective Study Examining the Role of Gestational SSRI Exposure in the Development of Functional Gastrointestinal Disorders
Abstract Functional gastrointestinal disorders (FGIDs) are common, costly, and cause significant impairment that can begin in infancy. FGIDs remain poorly understood, and treatment...
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease
OVERALL ? SUMMARY Alzheimer?s disease (AD) is a major unresolved public health problem.Efforts to prevent or stall this disease have failed, in good part because of inadequate unde...
Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection Fraction
Project Summary/Abstract Heart failure (HF) is a major public health problem worldwide, and half of patients presenting with HF have preserved ejection fraction (HFpEF), rather tha...
The Role of RBC Reactive Oxygen Species in Regulating Thrombotic Events During Aging
The Role of RBC Reactive Oxygen Species in Regulating Thrombotic Events During Aging Abstract: Seventy percent of mid-life stage (older) adults have already been diagnosed with at...
Stricker Learning Span: A Computer Adaptive Word List Memory Test Optimized for Remote Assessment
PROJECT SUMMARY/ABSTRACT Due to COVID-19, remote cognitive assessment has transitioned from an important research aim to an immediate and urgent research and clinical need.This nee...
A tailored exposure intervention targeting exercise anxiety and avoidance in cardiac rehabilitation
PROJECT SUMMARY/ABSTRACT Regular exercise and lifestyle physical activity (PA) are critical for quality of life and longevity among a growing aging population.Aging produces change...
Exosome biology in Alzheimer's disease and concussion
ABSTRACT Repeated concussions (mild Traumatic Brain Injury, mTBI), which are particularly prevalent in athletes and military personnel, can lead to long-term brain health issues in...
Sex Differences in the Clinical Expression of Alzheimer's Disease Neuropathology and Their Underlying Biological Mechanisms
PROJECT SUMMARY/ABSTRACT Sex differences in the risk of Alzheimer’s disease (AD) and AD pathology burden have been extensively studied; however, little is known about how AD pathol...
Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease
OVERALL – SUMMARY Alzheimer’s disease (AD) is a major unresolved public health problem. Efforts to prevent or stall this disease have failed, in good part because of inadequate und...
Exosome biology in Alzheimer's disease and concussion
ABSTRACT Repeated concussions (mild Traumatic Brain Injury, mTBI), which are particularly prevalent in athletes and military personnel, can lead to long-term brain health issues in...
Understanding and Improving Inequities in Palliative Care for Older Adults with Advanced Dementia and Limited-English Proficiency: A Mixed-Methods Evaluation
PROJECT SUMMARY Older adults with Alzheimer's Disease and Related Dementias and limited-English proficiency (LEP) are at high risk of receiving suboptimal, goal-discordant car...
A tailored exposure intervention targeting exercise anxiety and avoidance in cardiac rehabilitation
PROJECT SUMMARY/ABSTRACT Regular exercise and lifestyle physical activity (PA) are critical for quality of life and longevity among a growing aging population. Aging produces chang...
Impact of Sleep Duration on Immune Balance in Urban Children with Asthma
Project Summary / Abstract Urban children with asthma are at high risk for short sleep, due to an environment that jeopardizes sleep and asthma management. Further, this group suff...
Clinical Core
Clinical Core Project Summary The theme of the Penn ADRC is to better understand both the upstream factors and processes that contribute to Alzheimer?s Disease (AD) heterogeneity a...
Towards Objective Metrics to Quantify the Role of HIV and Increasing Cognitive Demand on Instrumental ADLs in People Aging with HIV
PROJECT SUMMARY About 37 million people are living with HIV (PLWH) worldwide.As they age and their HIV status becomes more chronic, they face new challenges associated with the chr...
Testing a very low-carbohydrate diet version of the Diabetes Prevention Program to reduce risk factors for type 2 diabetes
ABSTRACT One-third of U.S. adults have prediabetes and are at high risk of developing type 2 diabetes and its devastating health consequences.The landmark Diabetes Prevention Progr...