Results for Health
130,725 grants found
Showing 127,621 – 127,640 of 130,725 grants for "Health"
Influence of Age and Sex on Cerebral Edema Formation Following Traumatic Brain Injury
Traumatic brain injury (TBI) is a serious public health concern. After TBI, elderly patients suffer from higher mortality rate and worse functional outcome compared to young patien...
Hyperphosphatemia Contributes to Skeletal Muscle Atrophy in the Absence and Presence of Chronic Kidney Disease
PROJECT SUMMARY Chronic kidney disease (CKD) is a health epidemic that increases risk of death due to various comorbidities. Alterations in mineral metabolism are a hallmark of adv...
Post-transcriptional regulation of germline mRNAs in C. elegans
Project Summary: My lab is interested in defining how the maternal load is established during oogenesis and decoded after fertilization. We know the identity of most important mate...
Implementation of Continuum of Care Sepsis Phenotyping and Risk Stratification
PROJECT SUMMARY/ABSTRACT This proposal outlines a 5-year research and career development plan for Dr. Gabriel Wardi, an emergency medicine intensivist and assistant professor at UC...
Improving Self-Regulation and Social Support for Type 1 Diabetes During Emerging Adulthood
PROJECT SUMMARY Type 1 diabetes (T1D) is a significant public health problem, with some three million Americans living with the illness. Although extensive research has examined fa...
Discovery of Novel Anti-inflammatory, Non-immunosuppressive Molecules forMitigation of Cytokine Storm in COVID-19 Patients
Project Summary/Abstract The World Health Organization has reported over 216 million confirmed cases of COVID-19 infections and over 4.5 million deaths world-wide as of August 31,...
Translational Studies of the Short-Chain Fatty Acid Acetate for Improving Age-Associated Arterial Dysfunction
PROJECT SUMMARY/ABSTRACT The purpose of this K99/R00 application is to provide support for Dr. Vienna Brunt, a promising postdoctoral fellow in the laboratory of Dr. Douglas Seals,...
Spatiotemporal control of ubiquitination by phosphoinositide-binding proteins
Project Summary/Abstract Progression through the cell cycle involves spatiotemporal coordination of cytoskeletal and membrane dynamics with controlled proteolysis events. The anaph...
A novel psychological-behavioral intervention to promote physical activity after acute coronary syndrome
Despite the clear benefits of physical activity on recovery and survival following an acute coronary syndrome (ACS), most of the 1 million Americans suffering an ACS each year are...
Collaborative Research: Integrative Modeling, Prediction, and Validation of Multi-Scale Dynamics for Three-Dimensional Chromatin Structures in Cell Differentiation
This interdisciplinary award develops mathematical models and computational algorithms to dissect the mechanisms of how different types of cells are formed from stem cells. The for...
CRII: OAC: Cyberinfrastructure for Machine Learning on Multivariate Time Series Data and Functional Networks
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).From weather analysis to brain region activity analysis, from traffic flow an...
CAREER: Learning and Using Community-Driven Natural Language Processing Models
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).There is a growing interest in applying Natural Language Processing (NLP) to...
CAREER: Microbial regulation of plant coexistence and invasive dominance: changes with environmental stress
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).Thousands of microorganisms (e.g., fungi, bacteria) live in soil, in and arou...
Influence of Age and Sex on Cerebral Edema Formation Following Traumatic Brain Injury
Traumatic brain injury (TBI) is a serious public health concern. After TBI, elderly patients suffer from higher mortality rate and worse functional outcome compared to young patien...
Translational Studies of the Short-Chain Fatty Acid Acetate for Improving Age-Associated Arterial Dysfunction
PROJECT SUMMARY/ABSTRACT The purpose of this K99/R00 application is to provide support for Dr. Vienna Brunt, a promising postdoctoral fellow in the laboratory of Dr. Douglas Seals,...
Improving Self-Regulation and Social Support for Type 1 Diabetes During Emerging Adulthood
PROJECT SUMMARY Type 1 diabetes (T1D) is a significant public health problem, with some three million Americans living with the illness. Although extensive research has examined fa...
CAREER: Randomized Multiscale Methods for Heterogeneous Nonlinear Partial Differential Equations
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).Heterogeneous systems with salient features at multiple scales are ubiquitous...
The role of host-derived lipids in Mycobacterium tuberculosis infection
The bacteria Mycobacterium tuberculosis is a global killer causing over a million deaths from tuberculosis (TB) every year. It is therefore a major burden to human health. To reduc...
CoVPN 3003 A Phase 3 Study to Assess the Efficacy and Safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older LC 3
Project Abstract This proposal outlines the scientific agenda for the COVID-19 Prevention Network (CoVPN) Vaccines Leadership Operations Center (LOC) for implementation of the COVI...
A Randomized Controlled Trial of Prophylaxis with Direct-acting Antivirals for Kidney Transplantation from Hepatitis C virus-infected donor to Uninfected Recipients (PREVENT-HCV)
Due to epidemics of opioid overdose and hepatitis C virus (HCV), the availability of kidneys from HCV-viremic (HCV+) donors is increasing. There are limited numbers of HCV+ transpl...