Results for Health
130,725 grants found
Showing 127,701 – 127,720 of 130,725 grants for "Health"
Programming immune function through modular assembly of polyionic immune signals
Vaccination is one of the transformative advances of the last century, allowing prevention of infection with a single dose.However, vaccines for diseases that continue to challenge...
Neoadjuvant immunotherapy approaches to early stage melanoma
Project Summary – Project 3 There is an unmet need to improve the survival of patients with high-risk Stage II melanoma. Currently, the treatment for Stage II melanoma is surveilla...
Combining information from multiple circadian activity rhythm metrics to optimally detect mild cognitive impairment using a consumer wearable
Abstract: Widely-scalable methods for the earlier detection of elevated Alzheimer’s Disease and Related Dementia (ADRD) would enable earlier intervention and can help reduce/delay...
A clinical prediction rule for identifying South African colorectal cancer patients who will fail to engage in oncology care
PROJECT SUMMARY/ABSTRACT Colorectal cancer (CRC) is an emerging public health problem in South Africa (SA). Preliminary research from KwaZulu-Natal (KZN), SA shows that 23% of newl...
A clinical prediction rule for identifying South African colorectal cancer patients who will fail to engage in oncology care
PROJECT SUMMARY/ABSTRACT Colorectal cancer (CRC) is an emerging public health problem in South Africa (SA). Preliminary research from KwaZulu-Natal (KZN), SA shows that 23% of newl...
A clinical prediction rule for identifying South African colorectal cancer patients who will fail to engage in oncology care
PROJECT SUMMARY/ABSTRACT Colorectal cancer (CRC) is an emerging public health problem in South Africa (SA). Preliminary research from KwaZulu-Natal (KZN), SA shows that 23% of newl...
Exploring how the multi-disciplinary team supports people with Motor Neuron Disease making the decision to have gastrostomy feeding tube placed.
Background Motor neuron disease (MND) (also known as amyotrophic lateral sclerosis (ALS)), is a progressive neurological condition leading to the degeneration of the motor system a...
Targeting obesity to improve survival from childhood acute lymphoblastic leukemia
Obesity is a worldwide health challenge that increases the risk of developing and dying from multiple types of cancer. B-cell acute lymphoblastic leukemia (B-ALL) is the most commo...
Targeting obesity to improve survival from childhood acute lymphoblastic leukemia
Obesity is a worldwide health challenge that increases the risk of developing and dying from multiple types of cancer. B-cell acute lymphoblastic leukemia (B-ALL) is the most commo...
Mechanisms of Lipotoxic Arrhythmias
Project Summary/Abstract: High-fat diet induced lipotoxicity is an epidemic that poses a significant public health problem with over one-third of the world population being either...
Personalized Rejection Risk Assessment in Cardiac Transplantation
Project Summary: Cardiac allograft rejection (CAR) is a serious concern in transplant medicine, representing the leading threat to short- and long-term allograft survival.As a resu...
Dignity Therapy for Older Cancer Patients: Identifying Mechanisms and Moderators
PROJECT SUMMARY Nearly 600,000 older Americans die a cancer-related death each year. Maintaining human dignity is central to quality of life for patients with serious illness. Our...
Identifying and protecting alcohol-sensitive epigenetic changes in congenital heart disease
This proposal describes a five-year mentored research and training plan that will facilitate the development of Dr. Stephanie Ford, MD as an independent investigator in the pathoge...
Personalized Rejection Risk Assessment in Cardiac Transplantation
Project Summary: Cardiac allograft rejection (CAR) is a serious concern in transplant medicine, representing the leading threat to short- and long-term allograft survival. As a res...
Dignity Therapy for Older Cancer Patients: Identifying Mechanisms and Moderators
PROJECT SUMMARY Nearly 600,000 older Americans die a cancer-related death each year. Maintaining human dignity is central to quality of life for patients with serious illness. Our...
Urine cadmium and risk of fracture and bone loss
Urine cadmium and risk of fracture and bone loss Abstract Osteoporosis and related fractures are a major cause of morbidity and mortality in the United States and globally. Mechani...
Urine cadmium and risk of fracture and bone loss
Urine cadmium and risk of fracture and bone loss Abstract Osteoporosis and related fractures are a major cause of morbidity and mortality in the United States and globally. Mechani...
Vaginal microbiota transplant to promote Lactobacillus-dominant cervicovaginal communities
PROJECT SUMMARY Vaginal colonization with a Lactobacillus-dominant microbial community is associated with lower risk for preterm birth, HIV acquisition, HPV persistence and cervica...
Development of a digital intervention to address stigma among pregnant unmarried adolescents living with HIV
Project Summary/Abstract Kenya is one of few countries burdened by a combination of high rates of mother-to-child transmission (MTCT) of HIV, large numbers of adolescents living wi...
A multiscale approach for elucidating nuclear entry mechanisms of HIV-1 capsid
Project Summary Human immunodeficiency virus type 1 (HIV-1) remains a major threat to global health. Therefore, it is essential that we fully understand the mechanism of viral infe...