Results for Health
130,725 grants found
Showing 127,741 – 127,760 of 130,725 grants for "Health"
Characterizing the Genomic Basis of Immune-Mediated Resilience Against Tuberculosis in an Admixed Peruvian Population
Project Summary/Abstract Tuberculosis (TB) remains the global leading cause of death from an infectious agent.Understanding why some patients present with early symptoms while othe...
The Multifactorial Roles of Platelets in Uncomplicated Malaria Infection
Project Summary/Abstract The malaria causing Plasmodium parasite continues to be a major public health threat, with at least 230 million annual cases worldwide.Plasmodium vivax (P...
Overcoming the hurdles to successful CAR T cell therapy for a functional HIV cure
Project Summary/Abstract This proposal seeks the necessary funding to facilitate the career transition of Dr. Daniel Claiborne to an independent academic scientist.The original aim...
Cardiovascular Consequences of Duchenne and Becker Muscular Dystrophinopathies
ABSTRACT/PROJECT SUMMARY Duchenne and Becker muscular dystrophinopathies (DMD/BMD) have a mutation in the dystrophin gene that, together, represent over 80% of all cases of muscula...
Non-invasive hemodynamic sensor patch for remote, early detection and prevention of heart failure with left bundle branch block
1 Project Abstract 2 The long-term goal of this SBIR is to develop a remote, non-invasive early-warning system for heart 3 failure progression in presymptomatic patients at elevate...
Automated Contact Tracing System for Rapid High-Accuracy Assessment to Management Dementia Patients and Staff Exposed to Infectious Diseases in Long Term Care Facilities
Project Abstract In this Fast-Track SBIR project, ASTER Labs will address an urgent, immediate, need for accessible and accurate contact tracing to aid management of infectious dis...
Metalloprotein Mechanisms of Redox Regulation and Catalysis
Abstract for Metalloprotein Mechanisms of Redox Regulation and Catalysis This proposal covers the three R01 grants funding my laboratory and aims to fill gaps in understanding the...
Targeting added sugar to improve dietary intake in high-risk adolescents
PROJECT ABSTRACT The overall goal of this K01 proposal is to provide Gina Tripicchio, PhD, MSEd, with the training and mentorship to establish an independent program of research fo...
South Texas Alzheimer's Disease Center Clinical Core
Abstract The Mexican-American (MA) Hispanic community is the most rapidly growing minority and is disproportionately affected by Alzheimer?s disease and related dementias (ADRDs).N...
Efficacy of a self-advocacy serious game intervention for women with advanced cancer
Project Summary Individuals with cancer must overcome multiple, ongoing challenges (?self-advocate?) related to their cancer experience to receive patient-centered care.Women with...
Addressing the Needs of Key Subgroups of Caregivers of Persons with Dementia After Loss Using Self-Determination Theory: A Mixed Methods Approach
Project Summary / Abstract Within 10-years, most persons living with Alzheimer?s disease and related dementias (AD/ADRD; PLWD) will die, creating 13+ million new bereaved AD/ADRD c...
Integration of multimodal cancer predisposition genetic counseling practices within the pediatric oncology setting
PROJECT SUMMARY Recent advances have led to a rapid increase in the testing and identification of cancer predisposition in children.There is growing evidence that ?15% of childhood...
Development of perivascular space mapping toolset as a diagnostic aid for Alzheimer's disease
Project Summary Alzheimer?s disease (AD) is a devastating disease that affects millions of Americans and imposes a huge socio- economic burden.AD-related cognitive decline is assoc...
Scaling up tobacco control in India: Comparing smartphone to in-person training for implementing an evidence-based intervention to reduce tobacco use among schoolteachers
Project Summary: Tobacco-related deaths are rising rapidly in low and middle-income countries (LMICs). In India alone, tobacco use accounts for over 1.2 million deaths each year.Re...
Role of Zika virus (ZIKV) infection in glaucoma pathobiology
PROJECT SUMMARY The overall goal of this project is to investigate the role of Zika virus (ZIKV) in glaucoma pathobiology.ZIKV is an emerging viral pathogen that causes microcephal...
Host-microbiome interactions after lung transplantation and chronic lung allograft dysfunction
PROJECT SUMMARY/ABSTRACT This project describes a 5-year mentored career development plan with the goal of training the principal investigator to become an independent physician-sc...
New targeted BDNF nanoparticles for treatment of METH addiction and neurotoxicity
Methamphetamine use disorder (MUD) represents a major chronic health problem in the US and abroad.Magnetic Resonance Imaging (MRI) studies have consistently shown striatal structur...
Mapping the germinal center and memory B cell landscape to complex antigens
ABSTRACT Vaccines are one of the most successful public health interventions over the past century.Of the 28 licensed vaccines, nearly all of them work by induction of protective a...
SUCCEED Pilot Project 2
PILOT PROJECT 2: PROJECT SUMMARY The NCI Screen to Save (S2S) has successfully increased awareness about colorectal cancer (CRC) and the importance of screening for prevention and...
Vaginal microbiota transplant to promote Lactobacillus-dominant cervicovaginal communities
PROJECT SUMMARY Vaginal colonization with a Lactobacillus-dominant microbial community is associated with lower risk for preterm birth, HIV acquisition, HPV persistence and cervica...