Results for Health
130,725 grants found
Showing 127,781 – 127,800 of 130,725 grants for "Health"
Prediction of Heart Failure Onset using Multimodal Data Analysis, Deep Learning and Commercial Wearables
Prediction of Heart Failure Onset using Multimodal Data Analysis, Deep Learning and Commercial Wearables Project Summary/Abstract Research: Heart failure is one of the leading caus...
Fibrinolysis Dysfunction Impact on Graft Function in Liver Transplantation
PROJECT SUMMARY/ABSTRACT This is an application for a K99 award for Dr. Hunter Moore, a transplant surgery fellow at the University of Colorado School of Medicine. Dr. Moore is est...
Mapping the Time Course of mTORC1-Driven Tumorigenesis in the Developing Brain
SUMMARY The mammalian target of rapamycin complex 1 (mTORC1) signaling pathway regulates cell size and growth and is frequently mutated in disease, including in a class of neurodev...
Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting 1%-3% of the general population, with greater prevalence in older persons (8%-10%). AF is associ...
Generating novel predictive models to estimate the risk of future ASCVD & Dementia in older adults
Response to Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) Competition Title: Generating novel predictive models to estimate the risk o...
Integration of multimodal cancer predisposition genetic counseling practices within the pediatric oncology setting
PROJECT SUMMARY Recent advances have led to a rapid increase in the testing and identification of cancer predisposition in children. There is growing evidence that ≥15% of childhoo...
Towards biomarkers of resiliency in the extremely preterm child: a multimodal neuroimaging study of brain and environment
Prematurity is a public health crisis impacting 10% of all births. There is significant risk for neurocognitive impairment, including language. This can adversely impact quality of...
Overcoming the hurdles to successful CAR T cell therapy for a functional HIV cure
Project Summary/Abstract This proposal seeks the necessary funding to facilitate the career transition of Dr. Daniel Claiborne to an independent academic scientist. The original ai...
Host-microbiome interactions after lung transplantation and chronic lung allograft dysfunction
PROJECT SUMMARY/ABSTRACT This project describes a 5-year mentored career development plan with the goal of training the principal investigator to become an independent physician-sc...
Cardiovascular Consequences of Duchenne and Becker Muscular Dystrophinopathies
ABSTRACT/PROJECT SUMMARY Duchenne and Becker muscular dystrophinopathies (DMD/BMD) have a mutation in the dystrophin gene that, together, represent over 80% of all cases of muscula...
Structure and Functionof a Parasitic TGF-beta Mimic, TGM
Project Summary Helminth parasites are a threat to global health, with nearly one-third of the world’s population currently infected, constituting a high disease burden amongst bot...
The Multifactorial Roles of Platelets in Uncomplicated Malaria Infection
Project Summary/Abstract The malaria causing Plasmodium parasite continues to be a major public health threat, with at least 230 million annual cases worldwide. Plasmodium vivax (P...
Characterizing the Genomic Basis of Immune-Mediated Resilience Against Tuberculosis in an Admixed Peruvian Population
Project Summary/Abstract Tuberculosis (TB) remains the global leading cause of death from an infectious agent. Understanding why some patients present with early symptoms while oth...
Automated Contact Tracing System for Rapid High-Accuracy Assessment to Management Dementia Patients and Staff Exposed to Infectious Diseases in Long Term Care Facilities
Project Abstract In this Fast-Track SBIR project, ASTER Labs will address an urgent, immediate, need for accessible and accurate contact tracing to aid management of infectious dis...
Metalloprotein Mechanisms of Redox Regulation and Catalysis
Abstract for Metalloprotein Mechanisms of Redox Regulation and Catalysis This proposal covers the three R01 grants funding my laboratory and aims to fill gaps in understanding the...
South Texas Alzheimer's Disease Center Clinical Core
Abstract The Mexican-American (MA) Hispanic community is the most rapidly growing minority and is disproportionately affected by Alzheimer’s disease and related dementias (ADRDs)....
Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting 1%-3% of the general population, with greater prevalence in older persons (8%-10%). AF is associ...
Addressing the Needs of Key Subgroups of Caregivers of Persons with Dementia After Loss Using Self-Determination Theory: A Mixed Methods Approach
Project Summary / Abstract Within 10-years, most persons living with Alzheimer’s disease and related dementias (AD/ADRD; PLWD) will die, creating 13+ million new bereaved AD/ADRD c...
Role of estrogen receptor-a in aging and sex-specific responses to 17a-estradiol
PROJECT SUMMARY/ABSTRACT Several pharmacological compounds have shown promise as interventional strategies for extending longevity. One recently studied compound shown to improve h...
New targeted BDNF nanoparticles for treatment of METH addiction and neurotoxicity
Methamphetamine use disorder (MUD) represents a major chronic health problem in the US and abroad. Magnetic Resonance Imaging (MRI) studies have consistently shown striatal structu...