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15,626 grants found
Showing 4,181 – 4,200 of 15,626 grants
REGULATION OF CARCINOGENIC HUMAN PAPILLOMAVIRUS GENE EXPRESSION
AIMS: Here we propose to explore the complex mRNA-splicing mechanisms of carcinogenic human papillomaviruses (HPVs) as targets for therapy to HPV-infections and cancer.We will also...
Embracing extreme weather and compound events in landscape planning: the case of reindeer husbandry in Northern Sweden
Chain reactions of extreme weather are among the most harmful consequences of climate change on the environment and society.However, the complexity and uncertainty involved in pred...
Neurodevelopmental disorders in children born preterm. Early identification and intervention
Preterm birth occurs in 6-12% of pregnancies globally.Intensive care of preterm infants has made major advance over the last decades resulting in dramatically increased survival ra...
Strengthening society’s ability to mitigate biodiversity loss from extreme weather events
The combination of both gradual climate change and the increase in frequency and magnitude of extreme weather events (EWEs) means that practitioners and policymakers need scientifi...
Defining the chromatin dynamics and its role in lymphatic vessel development and disease
Lymphatic vessels are no longer considered a passive conduit since their central role in a number of physiological processes has been determined. However, it is still unclear how t...
Early synaptic endosome dysfunction in Alzheimer disease: convergence of ApoE, Aβ & tau
Alzheimer disease (AD) is a heterogenous disease of aging brain with diverse influences including alterations in lipid, immune and protein degradative function.Our group contribute...
Deciphering multiple sclerosis disease processes along the disease course
Multiple sclerosis (MS) features aberrant adaptive immune reaction towards central nervous system antigens leading to myelin and neuron/axon damage.Disease modulatory therapies (DM...
SISTer’s Care: Co-deSIgn of STillbirth CARE in Benin and Malawi
Stillbirths are one of the most depressing realities of our time: Each year 2 million babies die before or during birth.Compassionate care from diagnosis, throughout hospital stay...
A self-management program to prevent falls in people with multiple sclerosis - a randomized controlled trial
The purpose is to evaluate the effects of a self-management fall prevention program for people with multiple sclerosis (PwMS):Is the program effective in reducing number of falls i...
Water stress in Swedish forests: identifying risk areas to target management action (WiSdoM)
Sweden’s forests are increasingly exposed to extreme heat and drought, causing periods of water stress.This trend is expected to intensify in the coming decades, with the risk of s...
Simplified cardiopulmonary resuscitation with chest compressions only compared to cardiopulmonary resuscitation with chest compressions and ventilations? A national randomized clinical survival trial
Research question: Is simplified cardiopulmonary resuscitation (CPR) using chest compressions only as good as CPR using both chest compressions and ventilations in out-of-hospital...
For an equal and sustainable menstrual health
Purpose and goal:The project aims to contribute to health and gender equality. This is done by implementing the entire value chain for the manufacture and distribution of an innova...
Long non-coding RNA as a fine tuner of fat cell function.
Energy is stored in the form of triglyceride ready for breakdown into fatty acids (FAs) and release into the circulation.In obesity, the adipose tissue dysfunctions, resulting in h...
Cell generation in the adult brain
The aim of the proposed projects is to answer key unresolved questions concerning cell generation in the adult brain, ranging from uncovering the cell types and molecular logic of...
Effects, measures and solutions for resilient housing to extreme heat
Increased and longer heat waves, together with higher average temperatures, have considerable effects on buildings and occupants’ comfort and health, particularly in housing, where...
Somatic disorders in individuals with autism: identification of biological and social risk factors
Autism is a common lifelong condition.Autistic individuals are at a high risk of somatic disorders, such as epilepsy, and are at an increased risk for premature mortality.A better...
Establishment of a body-wide non-coding RNA cell type enrichment atlas, with a focus on endothelial enriched non-coding gene function
In this proposal, we plan to generate a publicly accessible cell type specificity atlas for human non-protein coding RNAs (ncRNAs), and to investigate the function of those enriche...
Control of gene expression in human neuronal development and neuropsychiatric diseases
The overall aim is to understand brain development, especially in the context of neuropsychiatric disorders.We work now toward four Specific Aims: 1) We have identified 47351 activ...
Diversity and structure of pollinator-virus communities from metatranscriptomes
There is increasing concern about insects and pollinator decline in Europe but little is known about the role of infectious diseases.Research to date, focusing only on a few virus...
Unlocking the Protein Production Potential of Non-Conventional Yeasts with Artificial Intelligence
Non-Conventional Yeasts (NCYs) offer unique benefits for protein production over traditional model organisms due to their ability to metabolise complex carbon sources, exhibit favo...