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How can promotion of physical activity after stroke or transient ischemic attack work remotely? Evaluation of a digital tool to improve cardiovascular health and wellbeing
The overarching purpose is to improve secondary stroke prevention post stroke or transient ischemic attack (TIA) by increasing access to physical activity through telerehabilitatio...
What can gait features tell us about cognitive aging and dementia? A multidisciplinary approach towards precision medicine
Gait assessment seems a feasible tool to aid diagnostic and predictive approaches in dementia. Yet, the diverse characteristics of older individuals hinder its application in a cli...
Size as a driver of stem cell ageing and cancer
The failure to regenerate tissues with age underlies some of the most challenging health issues in elderly. A main contributor to this decline is the loss of stem cell function.Des...
B4GALNT3 - a specific regulator of bone metabolism
With increasing age of the population, Sweden and industrialized countries across the globe are facing a substantial increase in osteoporotic fractures, which account for considera...
Environmental and molecular drivers of chronic kidney disease of non-traditional origin
Agricultural workers in tropical regions suffer from a high burden of chronic kidney disease of non-traditional origin (CKDnt), with occupational heat stress increasingly seen as c...
Importance of the hologenome in the optimization of plant reproduction and pollinators’ nutrition.
Plant reproduction is essential to many key features of the biosphere.It is becoming evident that plants optimize most of their biological processes by recruiting specific microbes...
The role of public health interventions early in life for long-term cognitive health and dementia
Risk factors for dementia accumulate across the life-course.Correlation studies suggest already very early life health factors, such as pregnancy and birth complications, may affec...
Systemic governance in national SDG implementation: assessing the compatibility with legitimacy and accountability
Sustainability scientists and policy makers alike are increasingly concerned with the need for transformative change to tackle multifaceted and interconnected contemporary sustaina...
Functional studies of organelle contacts in Alzheimer´s disease
A large number of physiological processes are perturbed in Alzheimer’s disease (AD).These include damage to mitochondria and the endoplasmic reticulum (ER), disruption to axonal tr...
Characterise the immunological response of diabetic patients with chronic foot ulcers
Diabetic foot ulcer (DFU) requires frequent hospital visits, anti-biotic therapies, and surgical procedures.Not only this approach has debilitating consequences for patients and en...
The placenta as a novel target organ for PFAS toxicity - epidemiologic studies of Ronneby pregnancies
A well-functioning placenta is necessary for a healthy pregnancy.The supply of nutrients and hormones to the fetus is reduced when placental function is disturbed which can have se...
Translational identification of medication repurposing candidates for Alzheimer´s dementia
Dementia creates a great personal and societal burden and there are currently no treatments to stop memory loss. Many patients with dementia take medications to treat other conditi...
DEMENTIA AND KIDNEY DISEASE: EPIDEMIOLOGICAL APPROACHES TO RISK FACTORS AND TREATMENT STRATEGIES
Dementia causes increased morbidity and mortality as well as tremendous social burden, but the treatment strategies are limited.Dementia can be prevented, and one-third of Alzheime...
Water intake and seasonal environmental stressors in cardiometabolic disease (WISECARD): identifying causes and opportunity for preventive intervention
Metabolic diseases are major health problems worldwide and increases the risk of cardiovascular disease (CVD). Several studies have observed marked seasonality of incident CVD and...
Deciphering the genetic architecture underlying valvular heart disease in dogs - A multidisciplinary project to improve cardiac health
The valvular heart disease myxomatous mitral valve disease, MMVD, is the most common heart disease in dogs and the disease is also affecting around 2-3% of the human population.MMV...
Extracellular vesicles as biomarkers, therapeutic targets and therapeutic vehicles for precision medicine
Extracellular vesicles (EV) are natural 30-100 nm nanovesicles released by all cells, and can stimulate or inhibit activation of immune cells depending on their cellular origin. Ca...
Can translocation of deadwood help help preserve wood-living metacommunities and ecosystem functions?
Translocation of species and substrates is a novel method increasingly used in ecological compensation and restoration, to possibly circumvent the “field of dreams” dilemma and mit...
Structural safety of corroded reinforced concrete structures from visual inspection
Which ageing civil engineering structures are still safe to use? This question urgently requires answers.We will enable assessment of the safety of deteriorated reinforced concrete...
Prevention and treatment of late complications after cranial radiation therapy
Childhood brain tumour survivors, particularly those treated with craniospinal radiotherapy, often pay a high price in the form of debilitating cognitive and other deficits. There...
Facilitating Early Diagnosis of Lung Cancer: Transdisciplinary Efforts Combining Data from Patient-Reports, Biomarkers and Imaging
This nursing science precision health project, focus on complex interactions among biological, social, and behavioural factors, and their effects on outcomes.By researching patient...