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15,626 grants found
Showing 10,821 – 10,840 of 15,626 grants
Stem cell based strategies to preserve fertility in boys and men.
To date, existing experimental models of spermatogenesis often lack the versatility to study the fundamental processes of spermatogenesis necessary to develop clinically relevant s...
Energy crisis in muscle cells - genetics and pathogenesis
The goals of this precision medicine project are to characterize the pathogenesis of new glycogen storage diseases discovered by us and to investigate the molecular background of t...
Ribosome biogenesis and new specialized ribosomes drives cancer cell plasticity
Currently there are no effective treatments that can cure metastatic breast cancer. One critical tumor cell plasticity program underlying metastatic spread is Epithelial-to-Mesench...
Survival and axillary recurrence following sentinel node-positive breast cancer without completion axillary lymph node dissection – the randomized SENOMAC trial
The role of completion axillary lymph node dissection (ALND) in sentinel node (SN)-positive breast cancer is questioned since key randomized trials showed no survival differences c...
Induction of β-cell neogenesis for future management of diabetes
For almost a century we have been able to control diabetes with insulin injections, yet we still have no cure. One possible way to cure diabetes is by increasing the number of insu...
Dysglycemia and IAPP/alpha-synuclein cross-seeding: key triggers for beta-cell amyloid formation during development of Type 2 diabetes?
Type 2 diabetes (T2D) belongs to the group of protein misfolding diseases where aggregation and accumulation of misfolded proteins into amyloid is a hallmark.Although, IAPP is the...
Media trust and social imaginaries: A qualitative study on the meaning and formation of media trust
What does it mean to trust the media? And how is trust (and mistrust) in the media formed in the everyday life of Swedish citizens?These questions will be explored in this research...
Managing Organizational Culture in Times of Workplace Digitalization
This research project investigates how organizational culture is created and managed in relation to ongoing pressures of workplace digitalization.As our working lives are increasin...
A New Interdisciplinary Framework for Studying the Relation between Climate Change and Migration
The program aims to establish a bold interdisciplinary research environment comprising the natural and social sciences to examine how climate change affects migration processes in...
Sport Without Injury ProgrammE (SWIPE) – promoting safe participation in community level sports
The main purpose of this 4-year research program is to investigate approaches to reduce injury risks and negative health consequences from partaking in community level sports. We u...
Enabling precision medicine in multiple sclerosis
Multiple sclerosis (MS) is a debilitating disease, mainly affecting young people and women. Untreated, it leads to severe disability and premature death.The cause of MS is largely...
Landscapes, Land Use and Connectivity in Ancient Attica, ca. 700–100 BCE
In the project, we will use new methods to examine the intensity and content of agricultural land use in Attica from the Archaic to the Hellenistic period (ca. 700–100 BCE), consid...
Studies of selenoprotein functions in health and disease
Cellular reduction and oxidation (redox) processes are crucial determinants for physiological as well as pathological processes. Selenoproteins play particularly important roles in...
Tourism Governance and the Making of Europe (1918–1957)
This project examines the intertwining of tourism governance, mobility, and diplomacy. We argue that, between 1918 and 1957, tourism played a crucial role in European integration.D...
Trials and observations: Using real world data to extend results from randomized trials in populations with acute coronary syndromes
Randomized trials do not estimate treatment effects in individuals that were eligible but did not enroll in the trial. However, guidelines established as a result of the trials app...
Epigenetics, chromatin remodeling in cellular quiescence and cancer
The goal of this 5-year project is to understand the specific functions of chromatin remodeling factors in cellular quiescence and cancer.Cellular quiescence is a reversible differ...
Discovering conformational convergence in cancer proteins through computer simulations and experiments
Cancer is a unique disease in which cells acquire positive traits for survival, mirroring species evolution.Classical methods to identify driver mutations aim to detect the signatu...
Integrated understanding of the pathophysiology in severe psychiatric disorders – a translational approach with focus on immune activation.
Our research aims to deepen our understanding of psychiatric disorders, particularly regarding the role of immune activation in the development of psychosis, cognitive impairments,...
Animal protection and welfare monitoring using multi-sensor technology and computer vision
Precision livestock farming offers unprecedented possibilities for monitoring of animal protection and welfare, capitalizing on the rapid digitalization, collection of Big Data and...
Clinical effectiveness of "Training for Awareness Resilience and Action" (TARA) compared to standard treatment for adolescents and young adults with depression- a randomized controlled trial
The purpose is to improve treatment of depressive disorders (DD) in youth.The primary aim is to compare the clinical effectiveness of a new treatment paradigm Training for Awarenes...