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44,293 grants found
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Can dynamic remodelling of fibrin fibres under load account for the remarkable mechanical properties of blood clots?
To fulfil its physiological role as the scaffold of blood clots, fibrin has large extensibility and strain stiffening behaviour, which make it deformable but tough at the same time...
Deciphering the structural and genetic intricacies of bacteriophage interaction with an AMR pathogen
Bacteriophage are both the most numerous biological entities on our planet; they are viruses that have evolved to exquisitely target bacterial pathogens with which they have co-evo...
Antibody-based Senolytics for Targeted Treatment of Lung Cancer and Respiratory Diseases
Main strategic BBSRC theme: Bioscience for an integrated understanding of health Secondary strategic BBSRC theme: Transformative technologiesSenescence is a natural cellular respon...
Ion trap-integrated optical cavities for fast networked quantum computation
The QCS vision of quantum computing using distributed modular processors (networked 'nodes') depends upon the rapid production of remote entanglement between nodes. The c...
Combining nMS and native TDMS to investigate the involvement of native human mu opioid receptor in depression.
This project falls within the EPSRC physical sciences research area. G-protein coupled receptors (GPCRs), such as the mu opioid receptor (MOR), amount to close to 40% of drug targe...
Foundations of Classical and Quantum Verifiable Computing
Recent years have seen a vast surge in the volume and sensitivity of data being generated and collected, e.g., in genetic sequencing, distributed storage services, and graphs of so...
Industrial CASE Account - The University of Manchester 2024
Doctoral Training Partnerships: a range of postgraduate training is funded by the Research Councils.For information on current funding routes, see the common terminology at https:/...
Evolving the adjacent possible for engineering design
The apparent optimality of evolution in the biological context has inspired the development of the so-called "nature-inspired methods", that can yield near-optima...
GABAergic inhibitory control of visual learning and attention in mouse models of schizophrenia
Main strategic BBSRC theme: Understanding the rules of life Secondary strategic BBSRC theme: Transformative technologies; Bioscience for an integrated understanding of healthThe br...
Go With Pride - Using AI to Connect the LGBTQ and Arts Communities
British theatre is dying: struggling to attract audiences, especially in UK regions, and losing major grants. And yet, there is a ready-made market for the Arts: * 50% of gay US tr...
Disentangling Responses of boreal ecosystems to climate change
Some of the fastest warming rates on earth occur in the northern hemisphere high-latitudes. As a result, we expect large changes in ecosystem functioning. Satellite observations re...
Synthetic Photoredox Catalysis
In contrast to the conventional synthetic approaches mentioned above, we are working on the development of novel photoredox visible-light driven processes which allow the functiona...
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Border-Solidarities: Re-centring migrant autonomy and activism along the Balkan Route
As migrants seeking asylum continue to be violently repelled from western Europe through the Balkan route (Isakjee et al 2020, Bird et al 2021), this project seeks to make two sign...
Quark Matter in Neutron Star Mergers
The existence and location of a first order phase transition from nuclear to deconfined quark matter are one of particle physics's mostexciting unanswered questions. With the...
Advancing pharmaceutical carbohydrate manufacture by selective enzymatic oxidation
This project requires an ambitious student with a background in chemistry or biochemistry to help us to develop novel approaches to drug manufacturing through biocatalysis. Green a...
Identifying cognitive and neurological markers of prodromal dementia: A novel, targeted functional connectivity approach
Advances in medical and social care has resulted in greater life-expectancy and an increasingly aging population across communities (1). However, dementia syndromes pose a signific...
The autistic inclusivity of music conservatoires: an ethnographic analysis of high-level musical learning environments and the wellbeing of their auti
This project will shed light on the wellbeing of autistic students within UK music conservatoires, investigating difficulties encountered by such students and analysing whether the...
Investigating Europa's Habitability ahead of Europa Clipper/Juice
Europa is one of Jupiter's largest moons, it has an active icy shell crust over a global liquid water ocean. The ocean is likely sustained through tidal heating due to its ecc...
Ideophone mechanics: a cross-linguistic study of iconic meaning mapping
Ideophones are an open word class found in many of the world's languages whose members depict sensory imagery using non-arbitrary association between sound and meaning (Dingem...