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44,293 grants found
Showing 41,381 – 41,400 of 44,293 grants
Using genetics to understand changes in body weight over time and links to disease.
My research will go beyond existing studies to establish a better understanding of the relationship between weight fluctuation and diseases linked to obesity, including type 2 diab...
Investigating the Therapeutic Potential of Anti-Human PDGFR-beta mAb In the Treatment of Rheumatoid Arthritis (RA)
During my visit, we will be investigating the therapeutic efficacy of anti-human PDGFR-beta in inhibiting PDGF-BB-driven synovitis and follicular dendritic cell (FDC) differentiati...
Immune cell-mediated de novo steroid biosynthesis in the tumour microenvironment dysregulates anti-tumour immunity
BACKGROUND Established tumours often foster an immunosuppressive microenvironment.Therefore, the major challenge in developing cancer-immunotherapy is to discover the anti-tumour i...
Genomic signatures in cell-free DNA and their role in early detection of cancer
Cancer can be treated with curative intent when diagnosed in its early stages. Attention has focussed increasingly on the use of circulating tumour DNA (ctDNA). Work by our group a...
CRUKD/21/004 : DETERMINE (aDvancing gEnomically maTchEd tReatMents IN rare cancErs)
Background: The increased uptake of Next Generation Sequencing in the clinic presents an opportunity to identify genomic alterations in adult cancers, paediatric and teenage young...
AION: A UK Atom Interferometer Observatory and Network
The AION project harnesses a new generation of quantum sensors to conduct experiments in fundamental physics, such as the discovery of dark matter, and detect hitherto unknown sour...
Synalogik: Detecting and challenging Local Government Authority (LGA) Fraud committed by Organised Criminal Groups (OCG) through Investigation Process Automation
Formed in 2018, SYNALOGiK Innovative Solutions Limited is a UK based technology company, founded by experts in data science, intelligence, security and investigation. Alpha-test ve...
Extreme volumetric imaging using single-shot optical tomography with compressive sensing
Standard approaches to 3D imaging typically rely on taking a series of 2D images one after another and reconstructing the 3D volume. This puts an upper limit on the volumetric fram...
Dark-dwellers as more-than-human misfits: a new synthesis of disability studies, environmental history and histories of human-animal relations.
There are at least a billion people on this planet who possess 'misfitting' bodies and who are consequently directly affected by disability. Many more people encounter di...
Scaling up the production of bio-based and biodegradable packaging for the cosmetics industry
Annual global plastic production reached 438 million metric tonnes in 2017 (Geyer\_2020). Each year, it is estimated that at least 8 million metric tonnes of plastic waste reaches...
University of Central Lancashire and 1st Technologies Limited
To develop a unique integrated software suite of automatable tools to refurbish and repurpose used IT equipment more efficiently so increasing productivity, sales and reducing e-wa...
AQUALINE - High Performance Thermoplastic Prepregs using Aqueous Impregnation
Thermoplastic composites are gaining popularity in aerospace and other sectors.In this project, an environmentally safe process will be demonstrated which allows a wide variety of...
Thermochemical remanent magnetisations: How do they affect ancient magnetic field intensities from the Earth and Solar System?
Ancient records of magnetic fields stored in rocks and meteorites hold the key to answering some of the most fundamental questions in Earth and Planetary Sciences including the evo...
Novel Control Approaches to Complex Aircraft Dynamics project, abbreviated to NOMAD 01
Scope changeAs per our previous briefings, unfortunately, we have had to revise the scope of this project due to our supplier of airframes no longer being in a position to do so in...
Anglia Ruskin University and Detoxpeople Limited
To embed the development, analysis and knowledge of liposomal formulation - both dry and liquid - facilitating future product design and the adoption of a scaled up manufacturing p...
The Glider
Established in 2001, UK-based SME Buckingham Healthcare (Buckingham) has a team with significant clinical expertise and a strong track record in researching, developing and commerc...
Decarbonising Precast Concrete Manufacturing
The **Decarbonising Precast Concrete Manufacturing** project is to deliver a comprehensive feasibility study for implementing deep decarbonisation interventions at Laing O'Rou...
Novel Grinding Technology with Advanced Cooling Capabilities Abstract
The project aims to develop a novel cooling capability in machining operations. During the grinding process friction can cause the generation of heat which affect the workpiece int...
An innovative cost saving solution for 100 years of nuclear waste containment
**Vision:** A containment solution for domestic and international nuclear waste management and decommissioning markets, specifically targeting unshielded legacy and new build waste...
Centre for Rapid Online Analysis of Reactions (ROAR), Phase II
The Centre for Rapid Online Analysis of Reactions (ROAR) at Imperial College London was established in 2018, with the award of a strategic equipment grant, and offers three main ca...