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Results for Health

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Showing 127,021127,040 of 130,725 grants for "Health"

Active NON-SBIR/STTR RPGS
Genetic and Neuronal Mechanisms that Regulate Zebrafish Sleep
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... California Institute of Technology United States 2021 – 2029

ABSTRACT Sleep disorders are pervasive, contribute to morbidity in several psychiatric disorders, and cause an annual economic burden of $100 billion. However, despite its importan...

$8.89M
USD
Completed NON-SBIR/STTR RPGS
Meeting the Challenges of COVID-19 by Expanding the Reach of Palliative Care: Proactive Advance Care Planning with Videos for the Elderly and all Patients with Dementia
NATIONAL INSTITUTE ON AGING Boston Medical Center United States 2021 – 2023

The majority of patients aged 65 or over, and patients with Alzheimer's Disease and Related Dementias (ADRD), have never communicated their preferences to clinicians or comple...

$24.87M
USD
Completed SBIR-STTR RPGS
Commercialization of SciDAP, a next generation universal platform for collaborative data analysis
NATIONAL HUMAN GENOME RESEARCH INSTITUTE Datirium, Llc United States 2021 – 2022

Summary The recent proliferation of next-generation sequencing (NGS) - based methods for the analysis of gene expression, chromatin structure and protein-DNA interactions has creat...

$520K
USD
Completed NON-SBIR/STTR RPGS
University of Rochester Vaccine and Treatment Evaluation Unit (VTEU)-mRNA-1273-P204 Moderna Pediatric Study
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of Rochester United States 2021 – 2022

The Vaccine and Treatment Evaluation Units (VTEUs) are a critical resource for the NIAID Infectious Diseases Clinical Research Consortium to conduct clinical research and trials to...

$11.44M
USD
Completed OTHER RESEARCH-RELATED
The Nathan Schnaper Intern Program in Translational Cancer Research
NATIONAL CANCER INSTITUTE University of Maryland Baltimore United States 2021 – 2026

Significant progress in detection and treatment has reduced cancer mortality rates; however, with over 1.7 million new cases and 600,000 deaths from cancer reported in 2019, it rem...

$3.11M
USD
Active NON-SBIR/STTR RPGS
Genetic and Neuronal Mechanisms that Regulate Zebrafish Sleep
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... California Institute of Technology United States 2021 – 2029

ABSTRACT Sleep disorders are pervasive, contribute to morbidity in several psychiatric disorders, and cause an annual economic burden of $100 billion. However, despite its importan...

$12.56M
USD
Completed NON-SBIR/STTR RPGS
The role of Tmem263 in regulation of bone mass and strength
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETA... Indiana University Indianapolis United States 2021 – 2024

Our previous genome-wide association study identified 56 loci that were associated with bone mineral density (BMD) and fracture risk in men and women. One locus on chromosome 12q23...

$1.73M
USD
Completed NON-SBIR/STTR RPGS
Characterizing resilience to food-cue induced overeating in children
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Pennsylvania State University, The United States 2021 – 2025

Project Summary: While strong empirical evidence shows that exposure to food advertisements increases short-term food intake and contributes to the development of obesity, not all...

$6.04M
USD
Completed NON-SBIR/STTR RPGS
Transport, substrate specificity and regulation mechanisms of the ZIP transition metal transporters
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Michigan State University United States 2021 – 2026

Transport, substrate specificity and regulation mechanisms of the ZIP transition metal transporters Abstract Some d-block transition metals (Fe, Zn, Mn, Cu, Co, Mo and Ni) play key...

$2.78M
USD
Completed NON-SBIR/STTR RPGS
Characterizing resilience to food-cue induced overeating in children
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Pennsylvania State University, The United States 2021 – 2025

Project Summary: While strong empirical evidence shows that exposure to food advertisements increases short-term food intake and contributes to the development of obesity, not all...

$5.75M
USD
Completed NON-SBIR/STTR RPGS
The role of Tmem263 in regulation of bone mass and strength
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETA... Indiana University Indianapolis United States 2021 – 2023

Our previous genome-wide association study identified 56 loci that were associated with bone mineral density (BMD) and fracture risk in men and women.One locus on chromosome 12q23....

$2.09M
USD
Completed NON-SBIR/STTR RPGS
Meeting the Challenges of COVID-19 by Expanding the Reach of Palliative Care: Proactive Advance Care Planning with Videos for the Elderly and all Patients with Dementia
NATIONAL INSTITUTE ON AGING Boston Medical Center United States 2021 – 2022

The majority of patients aged 65 or over, and patients with Alzheimer's Disease and Related Dementias (ADRD), have never communicated their preferences to clinicians or comple...

$9.29M
USD
Completed OTHER RESEARCH-RELATED
Mechanisms of Prophage-Mediated Virulence Driving Community-Acquired MRSA Contagion
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... New York University School of Medicine United States 2021 – 2026

PROJECT SUMMARY Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is known to cause severe bacterial infections and spreads rapidly, creating outbreaks that...

$1.99M
USD
Completed OTHER RESEARCH-RELATED
Mechanisms of Prophage-Mediated Virulence Driving Community-Acquired MRSA Contagion
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... New York University School of Medicine United States 2021 – 2026

PROJECT SUMMARY Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is known to cause severe bacterial infections and spreads rapidly, creating outbreaks that...

$1.99M
USD
Completed NON-SBIR/STTR RPGS
Pathophysiology of Diabetic Gastroparesis
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Mayo Clinic Rochester United States 2021 – 2025

PROJECT SUMMARY/ABSTRACT Diabetes mellitus is associated with multiple complications including diabetic gastroparesis.The systemic effects of diabetes modify all cells in the body...

$5.39M
USD
Completed OTHER RESEARCH-RELATED
Tailored siRNA delivery to human endothelium to inhibit and reverse inflammatory damage following ischemia reperfusion injury in the kidney
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Yale University United States 2021 – 2023

Abstract Ischemia reperfusion injury (IRI) causes endothelial inflammation and microvascular rarefaction that leads to adverse kidney graft outcomes in organ transplant.Direct trea...

$1.06M
USD
Completed NON-SBIR/STTR RPGS
Evaluation and Optimization of a Just-in-Time Messaging Intervention to Reduce Alcohol-Facilitated Intimate Partner Violence Perpetration Among At-Risk Young Adult Men and Women
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Georgia State University United States 2021 – 2026

PROJECT SUMMARY Young adult men and women perpetrate intimate partner violence (IPV) at high rates.A summary of over 30-years of research concludes that alcohol is a causal factor...

$5.92M
USD
Completed NON-SBIR/STTR RPGS
Pathophysiology of Diabetic Gastroparesis
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Mayo Clinic Rochester United States 2021 – 2025

PROJECT SUMMARY/ABSTRACT Diabetes mellitus is associated with multiple complications including diabetic gastroparesis. The systemic effects of diabetes modify all cells in the body...

$5.53M
USD
Completed NON-SBIR/STTR RPGS
A new mouse model of severe asthma
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of North Carolina Chapel Hill United States 2021 – 2023

Project Summary Severe asthma comprises ~10% of all asthma cases but accounts for a disproportionately high degree of asthma health care costs and causes substantial decrements in...

$1.94M
USD
Completed OTHER RESEARCH-RELATED
Mechanisms of Prophage-Mediated Virulence Driving Community-Acquired MRSA Contagion
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... New York University School of Medicine United States 2021 – 2026

PROJECT SUMMARY Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is known to cause severe bacterial infections and spreads rapidly, creating outbreaks that...

$1.99M
USD